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  About Embracing BRCA  

A platform designed to help you understand more about BRCA gene mutations and its link to hereditary breast, ovarian, and prostate cancer.


What is a gene?

Genes are sections of our DNA that contain information which makes up each of us - our features and traits. This is why each and every one of us is unique just the way we are. Our genes are passed down to us from our parents when we are born. In the same way, we pass them down to our children. 1

Hereditary Breast, Ovarian, and Prostate Cancer & BRCA mutations

Did you know breast, ovarian, and prostate cancer can be inherited?

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Four Myths about BRCA

I already have cancer - Knowing my BRCA status won’t change anything.

Fact:
Knowing your BRCA status can help you make informed decisions about your treatment options, especially if you have cancer. In some cases, you may qualify for targeted therapies specific to your type of cancer. Additionally, it can inform your family members of their risk of developing cancer.

I don’t think I have a BRCA mutation since I don’t have a family history of cancer.

Fact:
Fact: Family history isn’t always a reliable predictor of either cancer risk or the presence of a BRCA mutation. In fact, a Malaysian study called the MAGIC study revealed that over half of ovarian cancer patients with BRCA mutations lacked a family history. This underscores the importance of BRCA testing, as it remains the only definitive way to confirm the presence of these mutations.

I don’t think I have a BRCA mutation since I had cancer at an older age.

Fact:
Age is not a predictor of whether a person has BRCA mutations for some cancers. In fact, a study conducted in Malaysia called the MaGiC study showed that there’s no correlation between age of diagnosis and the probability of carrying a BRCA mutation for ovarian cancer patients. For some cancers, regardless of the age of diagnosis or family history, it is never too late to get BRCA tested. 2-5

BRCA testing is only for women.

Fact:
Some cancers, like prostate and pancreatic cancer in men, can be linked to BRCA mutations. Men can also develop breast cancer and pass on BRCA mutations to their children. Understanding your BRCA status can therefore inform family members about their own cancer risk.

“Life is your canvas… so paint yourself a whole lot of colorful days!”

–– George Bellows ––

Genetic
Counseling

If you are interested to know more about BRCA genetic test, consult a genetic counselor for more information.

Learn more

References
  1. "DNA, Genes And Chromosomes — University Of Leicester". Www2.Le.Ac.Uk, 2020, https://www2.le.ac.uk/projects/vgec/schoolsandcolleges/topics/dnageneschromosomes.
  2. Yoon, S.Y.Y. et al. "Mainstreaming Genetic Counselling For Genetic Testing Of BRCA1/2 In Ovarian Cancer Patients In Malaysia (Magic Study)". Annals Of Oncology, vol 30, 2019, p. ix192. Elsevier BV, doi:10.1093/annonc/mdz446.010.
  3. Ledermann J, Raja F, Fotopoulou C, et al. Ann Oncol. 2013;24(6):vi24-vi32.
  4. Referenced with permission from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Genetic/Familial High-Risk Assessment: Breast and Ovarian V.2.2019. © National Comprehensive Cancer Network, Inc. 2018. All rights reserved. Accessed September 6, 2018.
  5. "Five Myths About BRCA Testing | Bebrcaware". Bebrcaware.Com, 2020, https://www.bebrcaware.com/what-is-brca/top-5-brca-testing-myths.html.
Enquiries? Contact our genetic counsellor